Select Publications

This book serves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.

Martinez, P., Mallo, D., Paulson, T. G., Li, X., Sanchez, C. A., Reid, B. J., ... & Maley, C. C. (2018). Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels. Nature communications, 9(1), 794.

Maley, C. C., Aktipis, A., Graham, T. A., Sottoriva, A., Boddy, A. M., Janiszewska, M., ... & Anderson, K. S. (2017). Classifying the evolutionary and ecological features of neoplasms. Nature Reviews Cancer, 17(10), 605.

Fortunato, A., Boddy, A., Mallo, D., Aktipis, A., Maley, C. C., & Pepper, J. W. (2017). Natural selection in cancer biology: from molecular snowflakes to trait hallmarks. Cold Spring Harbor perspectives in medicine, 7(2), a029652.

Martinez, P., Timmer, M. R., Lau, C. T., Calpe, S., del Carmen Sancho-Serra, M., Straub, D., ... & Naber, A. H. (2016). Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus. Nature communications, 7, 12158.

Andor, N., Graham, T. A., Jansen, M., Xia, L. C., Aktipis, C. A., Petritsch, C., ... & Maley, C. C. (2016). Pan-cancer analysis of the extent and consequences of intratumor heterogeneity. Nature medicine, 22(1), 105.

Abegglen, L. M., Caulin, A. F., Chan, A., Lee, K., Robinson, R., Campbell, M. S., ... & Jensen, S. T. (2015). Potential mechanisms for cancer resistance in elephants and comparative cellular response to DNA damage in humans. Jama, 314(17), 1850-1860.

Aktipis, C. A., Boddy, A. M., Jansen, G., Hibner, U., Hochberg, M. E., Maley, C. C., & Wilkinson, G. S. (2015). Cancer across the tree of life: cooperation and cheating in multicellularity. Philosophical Transactions of the Royal Society B: Biological Sciences, 370(1673), 20140219.

Walther, V., Hiley, C. T., Shibata, D., Swanton, C., Turner, P. E., & Maley, C. C. (2015). Can oncology recapitulate paleontology? Lessons from species extinctions. Nature Reviews Clinical Oncology, 12(5), 273.

Aktipis, C. A., Boddy, A. M., Gatenby, R. A., Brown, J. S., & Maley, C. C. (2013). Life history trade-offs in cancer evolution. Nature Reviews Cancer, 13(12), 883.

Greaves, M., & Maley, C. C. (2012). Clonal evolution in cancer. Nature, 481(7381), 306.